Thats for the players to decide :3
There are 122 official vaults, and only about 10 of them being "control" vaults, and over 50 vaults not even touched on by the series
For good RP sites, you gotta let the player get creative, IMO
canonically, there is a vault where the GECK mutated all the plants to grow extremely fast, and mutated the people in the vault into plant... things
Plant people, third race :3
theres vault 108 where everyone is a clone of Gary, although they may seem human, they are aggresive to non-clones, and each generation of clones was more aggressive than the last.
first generation Gary clone, fourth race :3
but if he's trying to keep the Fallout series canon...
im sorry, I couldnt type that out
Fallout is extremely renowned for releasing non-canon games, and non-canon plots
its whatever the fuck they want it to be, and whatever works for them